Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018111 | 0.91 | PAX8 (0.55) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL14384381 | 0.84 | PAX8 (0.50) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL3364970 | 0.84 | PAX8 (0.50) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL4015896 | 0.82 | PAX8 (0.49) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL15181430 | 0.82 | MT-CO2 (0.51) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL24448783 | 0.82 | NPSR1 (0.58) | PAX8BRD4CREBBPNPSR1RAB9A | |
| Water SCHEMBL27760152 | 0.82 | PAX8 (0.49) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL3368196 | 0.82 | PAX8 (0.49) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL1817649 | 0.82 | PAX8 (0.49) | PAX8BRD4CREBBPNPSR1RAB9A | |
| SCHEMBL25960282 | 0.82 | PAX8 (0.49) | PAX8BRD4CREBBPNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |