Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678335 | 1.00 | HRH4 (0.37) | HRH4HRH3ALDH1A1NTSR1PDE3B | |
| SCHEMBL25678336 | 1.00 | HRH4 (0.37) | HRH4HRH3ALDH1A1NTSR1PDE3B | |
| SCHEMBL25678339 | 0.92 | FFAR2 (0.41) | ALDH1A1CCR4SMN1; SMN2MEN1POLB | |
| SCHEMBL24123753 | 0.89 | HCRTR1 (0.38) | ALDH1A1PDE3BPDE3APDE10ASMN1; SMN2 | |
| SCHEMBL25675644 | 0.84 | HRH4 (0.40) | HRH4HRH3LCKKDRTEK | |
| SCHEMBL25675646 | 0.84 | HRH4 (0.40) | HRH4HRH3LCKKDRTEK | |
| SCHEMBL24123881 | 0.83 | KCNH2 (0.43) | ALDH1A1NTSR1CCR4TSHRPIM1 | |
| SCHEMBL16437252 | 0.82 | SMPD3 (0.42) | HRH4ALDH1A1PDE3BPDE3APDE10A | |
| SCHEMBL10203188 | 0.82 | FPR1 (0.41) | HRH4HRH3LCKKDRTEK | |
| SCHEMBL16437273 | 0.80 | MEN1 (0.42) | ALDH1A1PDE3BPDE3APDE10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |