Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935363 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL2641862 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL2641780 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL23387077 | 0.95 | ALDH1A1 (0.37) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL29259357 | 0.95 | ALDH1A1 (0.37) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL2636982 | 0.94 | FFAR1 (0.36) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL2636981 | 0.94 | FFAR1 (0.36) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL29770049 | 0.91 | ALDH1A1 (0.40) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL14935308 | 0.90 | FFAR1 (0.41) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR | |
| SCHEMBL14946474 | 0.90 | FFAR1 (0.41) | ALDH1A1MAPK1CYP3A4CYP2C9MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569276-A1 | NOVEL CATIONIC LIPIDS AND METHODS OF USE THEREOF | Protiva Biotherapeutics Inc. (CA) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011141705-A1 | NOVEL CATIONIC LIPIDS AND METHODS OF USE THEREOF | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2011-11-17 | — | — | WO | disclosed |