Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636981 | 1.00 | FFAR1 (0.36) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL14935617 | 0.94 | FAAH (0.40) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL2641862 | 0.94 | ALDH1A1 (0.41) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL2637018 | 0.94 | FAAH (0.40) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL2641777 | 0.94 | ALDH1A1 (0.41) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL14935616 | 0.94 | FAAH (0.40) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL2641780 | 0.94 | ALDH1A1 (0.41) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL2637017 | 0.94 | FAAH (0.40) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL14935363 | 0.94 | ALDH1A1 (0.41) | FFAR1FFAR4SOAT2SOAT1CYP3A4 | |
| SCHEMBL10081526 | 0.94 | SOAT2 (0.38) | SOAT2SOAT1CYP3A4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141703-A1 | COMPOSITIONS AND METHODS FOR SILENCING APOLIPOPROTEIN B | PROTIVA BIOTHERAPEUTICS INC. (CA) | 2011-11-17 | — | — | WO | disclosed |