SCHEMBL26418197

SCHEMBL26418197

Nc1nc(Nc2ccccc2)nc(Nc2ccc3[nH]c(=O)[nH]c3c2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ AURKA O14965 1/20 0.49
▸ AURKB Q96GD4 1/20 0.49
▸ JAK1 P23458 1/20 0.47
▸ JAK3 P52333 1/20 0.47
▸ KMT2A Q03164 4/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ TERT O14746 2/20 0.45
▸ MEN1 O00255 2/20 0.44
▸ GAA P10253 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ HBB P68871 1/20 0.44
▸ RHOA P61586 1/20 0.43
▸ CDK9 P50750 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23666321 0.83 MAPT (0.47) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL15501261 0.82 SNCA (0.52) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL21635741 0.80 DDX3X (0.55) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL21927159 0.80 AURKA (0.47) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL23139630 0.79 AURKA (0.43) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL13157227 0.78 JAK1 (0.49) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL2253957 0.77 GAA (0.69) MAPTALDH1A1KMT2ANPC1HTT
SCHEMBL21925305 0.76 AURKA (0.48) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL15501260 0.76 AURKA (0.51) MAPTALDH1A1AURKAAURKBJAK1
SCHEMBL21635756 0.75 BCL6 (0.56) MAPTALDH1A1AURKAAURKBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE SF1, SPIN1, RER1 MAPT 1234/4885ALDH1A1 1488/4885AURKA 4523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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