Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641914 | 0.82 | APP (0.40) | KCNH2HSD17B3RELAGRM5APP | |
| SCHEMBL2641829 | 0.82 | APP (0.40) | HSD17B3RELAGRM5APPMAPT | |
| SCHEMBL2641905 | 0.82 | NAPRT (0.40) | HSD17B3RELAGRM5APPMEN1 | |
| SCHEMBL2641919 | 0.82 | APP (0.40) | HSD17B3RELAGRM5APPMAPT | |
| SCHEMBL2278097 | 0.78 | P4HTM (0.58) | KCNH2HSD17B3APPMAPTMEN1 | |
| SCHEMBL2278107 | 0.78 | P4HTM (0.58) | KCNH2HSD17B3APPMAPTMEN1 | |
| SCHEMBL2641830 | 0.78 | BACE1 (0.40) | HSD17B3RELAGRM5MAPTMEN1 | |
| SCHEMBL17081899 | 0.78 | KCNH2 (0.58) | KCNH2RELAGRM5APPMAPT | |
| SCHEMBL2641822 | 0.76 | KCNH2 (0.47) | KCNH2GRM5MAPTMEN1KMT2A | |
| SCHEMBL2641817 | 0.76 | KCNH2 (0.47) | KCNH2GRM5MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |