Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641914 | 0.82 | APP (0.40) | NFE2L2MEN1KMT2AHSD17B3RELA | |
| SCHEMBL2641829 | 0.82 | APP (0.40) | ALDH1A1MEN1KMT2AHSD17B3RELA | |
| SCHEMBL2641820 | 0.82 | KCNH2 (0.50) | MEN1KMT2AHSD17B3RELAGRM5 | |
| SCHEMBL2641919 | 0.82 | APP (0.40) | MEN1KMT2AHSD17B3RELAGRM5 | |
| SCHEMBL12185997 | 0.81 | PAX8 (0.41) | NFE2L2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2373637 | 0.81 | MAPT (0.55) | ALDH1A1MEN1KMT2ALMNAHSD17B3 | |
| SCHEMBL2373640 | 0.81 | MAPT (0.55) | ALDH1A1MEN1KMT2ALMNAHSD17B3 | |
| SCHEMBL2641910 | 0.80 | MAPT (0.41) | NFE2L2ALDH1A1MEN1KMT2AHSD17B3 | |
| SCHEMBL2641830 | 0.78 | BACE1 (0.40) | ALDH1A1MEN1KMT2ALMNAHSD17B3 | |
| SCHEMBL4325573 | 0.76 | NAPRT (0.65) | NAPRTNFE2L2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |