Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641822 | 1.00 | KCNH2 (0.47) | KCNH2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2641913 | 0.79 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641833 | 0.79 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641908 | 0.79 | L3MBTL1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641902 | 0.79 | L3MBTL1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641827 | 0.79 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641917 | 0.79 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641915 | 0.79 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641924 | 0.79 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL2641820 | 0.76 | KCNH2 (0.50) | KCNH2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |