SCHEMBL26418362

SCHEMBL26418362

C/C=C\c1cc2c(cc1C)C(=O)OC2=O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
KMT2A Q03164 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HMGCR P04035 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20932349 1.00 KDM4E (0.36) KDM4ECYP1A2CYP2C19ALOX15TDP1
SCHEMBL23665496 0.80 ESR1 (0.32) KDM4ECYP1A2CYP2C19ESR1ESR2
SCHEMBL25516124 0.79 ALOX15 (0.32) ALOX15TDP1ALDH1A1
SCHEMBL1298310 0.76 ALOX15 (0.48) KDM4ECYP1A2CYP2C19ALOX15TDP1
SCHEMBL13891808 0.74
SCHEMBL28729858 0.72 ALOX15 (0.43) KDM4ECYP1A2CYP2C19ALOX15TDP1
SCHEMBL29518416 0.72 ALOX15 (0.43) KDM4ECYP1A2CYP2C19ALOX15TDP1
SCHEMBL29114004 0.69 CYP3A4 (0.39) CYP3A4HMGCR
SCHEMBL30613064 0.69 CYP3A4 (0.39) CYP3A4HMGCR
SCHEMBL27916371 0.69 CYP3A4 (0.39) CYP3A4HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE SF1, SPIN1, RER1 KDM4E 3761/4885CYP1A2 2158/4885CYP2C19 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.