Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641847 | 1.00 | SNCA (0.54) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL2641810 | 0.83 | SNCA (0.48) | SNCAAPPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27882977 | 0.83 | APP (0.55) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL12185951 | 0.83 | APP (0.56) | SNCAAPPMAPTMEN1NPC1 | |
| Iodide SCHEMBL27866683 | 0.81 | APP (0.54) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL2641781 | 0.81 | APP (0.54) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL2641903 | 0.81 | APP (0.62) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL2641907 | 0.81 | APP (0.62) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL2641774 | 0.81 | APP (0.54) | SNCAAPPMAPTMEN1NPC1 | |
| SCHEMBL32661415 | 0.80 | NFE2L2 (0.51) | NPC1RAB9ANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |