Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641953 | 0.85 | SNCA (0.46) | SNCANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2641852 | 0.84 | SNCA (0.46) | SNCANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2641877 | 0.84 | SNCA (0.48) | SNCANPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL2641847 | 0.83 | SNCA (0.54) | SNCANPC1RAB9ANFE2L2SMN1; SMN2 | |
| SCHEMBL2641843 | 0.83 | SNCA (0.54) | SNCANPC1RAB9ANFE2L2SMN1; SMN2 | |
| SCHEMBL12186029 | 0.83 | SNCA (0.43) | SNCANPC1RAB9ANFE2L2LMNA | |
| SCHEMBL2641940 | 0.80 | SNCA (0.42) | SNCALMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL32661415 | 0.76 | NFE2L2 (0.51) | NPC1RAB9ANFE2L2 | |
| SCHEMBL2641910 | 0.76 | MAPT (0.41) | SNCANPC1RAB9ANFE2L2SMN1; SMN2 | |
| SCHEMBL2641905 | 0.75 | NAPRT (0.40) | NFE2L2LMNASMN1; SMN2ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |