Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641953 | 0.85 | SNCA (0.46) | SNCAALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL2641877 | 0.84 | SNCA (0.48) | SNCAALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL2641810 | 0.84 | SNCA (0.48) | SNCAALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL2641781 | 0.83 | APP (0.54) | SNCATRIM24TRIM33ALDH1A1APP | |
| SCHEMBL2641774 | 0.83 | APP (0.54) | SNCATRIM24TRIM33ALDH1A1APP | |
| SCHEMBL12185981 | 0.83 | SNCA (0.41) | SNCATRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL2641940 | 0.80 | SNCA (0.42) | SNCAALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL2641868 | 0.76 | HDAC1 (0.58) | ALDH1A1APPEGFRRELAMAPT | |
| SCHEMBL2641829 | 0.75 | APP (0.40) | ALDH1A1APPEGFRRELAMAPT | |
| SCHEMBL2641850 | 0.73 | HDAC6 (0.46) | SNCATRIM24TRIM33CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |