Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641790 | 0.86 | MAPT (0.50) | SNCAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2641785 | 0.86 | MAPT (0.50) | SNCAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL12185978 | 0.85 | SNCA (0.39) | SNCAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2641953 | 0.81 | SNCA (0.46) | SNCAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8561733 | 0.80 | TAAR1 (0.47) | SNCAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2641810 | 0.80 | SNCA (0.48) | SNCAALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL2641877 | 0.80 | SNCA (0.48) | SNCAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2641852 | 0.80 | SNCA (0.46) | SNCAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2641871 | 0.79 | MAPT (0.39) | SNCAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2641830 | 0.78 | BACE1 (0.40) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |