Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19915930 | 0.83 | FGFR1 (0.62) | FGFR1KDRALDH1A1HTTSRC | |
| SCHEMBL2646769 | 0.83 | HTT (0.59) | FGFR1KDRALDH1A1HPGDHTT | |
| SCHEMBL1761842 | 0.82 | GABRA1 (0.55) | FGFR1KDRALDH1A1HPGDSRC | |
| SCHEMBL2642078 | 0.82 | FGFR1 (0.63) | FGFR1KDRALDH1A1HPGDSRC | |
| SCHEMBL2666380 | 0.82 | HPGD (0.52) | FGFR1KDRALDH1A1HPGDHTT | |
| SCHEMBL2642011 | 0.82 | HPGD (0.52) | FGFR1KDRALDH1A1HPGDHTT | |
| SCHEMBL24703671 | 0.81 | FGFR1 (0.75) | FGFR1KDRALDH1A1HPGDHTT | |
| SCHEMBL1762032 | 0.80 | GABRA1 (0.60) | FGFR1KDRALDH1A1HPGDMAPT | |
| SCHEMBL1668082 | 0.79 | GABRA1 (0.48) | FGFR1KDRALDH1A1HPGDSRC | |
| SCHEMBL1761905 | 0.79 | GABRA1 (0.48) | FGFR1KDRALDH1A1HPGDSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |