Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAPDH | P04406 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449714 | 0.82 | KDM4E (0.68) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL15581107 | 0.80 | KDM4E (0.58) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL9979780 | 0.74 | MAPT (0.46) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL27437406 | 0.71 | KDM4E (0.48) | KDM4EMAPTNQO2NPC1RAB9A | |
| SCHEMBL15581106 | 0.70 | KDM4E (0.46) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL10784379 | 0.69 | KDM4E (0.50) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL6206349 | 0.68 | NQO2 (0.71) | KDM4EMAPTNQO2NPSR1NPC1 | |
| SCHEMBL13388975 | 0.68 | NQO2 (0.72) | KDM4EMAPTNQO2NPC1RAB9A | |
| SCHEMBL24950993 | 0.67 | KDM4E (0.40) | KDM4EMAPTNQO2 | |
| SCHEMBL5678026 | 0.67 | HMGCR (0.45) | KDM4EMAPTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125359-A1 | COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125359-A1 | COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND | RAD51, UBE2D3, MDM2 | KDM4E 4361/4885MAPT 3319/4885NQO2 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.