Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644383 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDFGFR1MAPTKDR | |
| SCHEMBL16158430 | 0.80 | FGFR1 (0.86) | ALDH1A1HPGDFGFR1KDRMAOB | |
| Hydrochloric Acid SCHEMBL2641973 | 0.80 | ALDH1A1 (0.65) | ALDH1A1HPGDFGFR1MAPTKDR | |
| SCHEMBL2644889 | 0.79 | FGFR1 (0.80) | ALDH1A1HPGDFGFR1MAPTKDR | |
| SCHEMBL3342620 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDFGFR1MAPTHTT | |
| SCHEMBL30656825 | 0.78 | L3MBTL1 (0.57) | ALDH1A1HPGDFGFR1MAPTKEAP1 | |
| SCHEMBL26758082 | 0.78 | L3MBTL1 (0.57) | ALDH1A1HPGDFGFR1MAPTKEAP1 | |
| SCHEMBL2644783 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HPGDFGFR1MAPTLMNA | |
| SCHEMBL1679678 | 0.75 | MAPT (0.62) | ALDH1A1HPGDFGFR1MAPTNPC1 | |
| SCHEMBL24703671 | 0.74 | FGFR1 (0.75) | ALDH1A1HPGDFGFR1MAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |