Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306019 | 0.91 | FGFR1 (0.67) | FGFR1HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL16158487 | 0.88 | FGFR1 (0.55) | FGFR1HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL4015486 | 0.88 | HTT (0.71) | FGFR1HTT | |
| SCHEMBL2643550 | 0.84 | FGFR1 (0.78) | FGFR1HTTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2642014 | 0.83 | FGFR1 (0.76) | FGFR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL16158540 | 0.82 | FGFR1 (0.83) | FGFR1HTT | |
| SCHEMBL2642001 | 0.82 | FGFR1 (0.83) | FGFR1HTT | |
| SCHEMBL3417304 | 0.82 | HTT (0.78) | FGFR1HTT | |
| SCHEMBL2641988 | 0.81 | FGFR1 (0.59) | FGFR1HTTALDH1A1 | |
| SCHEMBL16158486 | 0.81 | FGFR1 (0.59) | FGFR1HTTKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | claimed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | claimed |
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |