⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19119332 | 0.98 | — | — | |
| SCHEMBL3949132 | 0.78 | — | — | |
| SCHEMBL11188780 | 0.73 | — | — | |
| SCHEMBL27337137 | 0.70 | CYP1A2 (0.35) | — | |
| Acetic Acid SCHEMBL28903973 | 0.65 | GABRP (0.33) | — | |
| SCHEMBL69399 | 0.65 | KDM4E (0.55) | — | |
| Acetic Acid SCHEMBL30664054 | 0.64 | — | — | |
| SCHEMBL70035 | 0.64 | KDM4E (0.59) | — | |
| SCHEMBL277059 | 0.61 | — | — | |
| SCHEMBL7767700 | 0.61 | KDM4E (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| EP-3551632-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | UNION THERAPEUTICS AS (DK) | 2024-06-12 | — | — | EP | claimed |
| EP-3523297-B1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | UNIV BERLIN FREIE (DE) | 2021-07-07 | — | — | EP | claimed |
| US-10683286-B2 | Furazan-3-carboxylic acid derivatives and use thereof in treatment of cancer | FREIE UNIVERSITAET BERLIN (DE) | 2020-06-16 | — | — | US | claimed |
| EP-3523297-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | Freie Universität Berlin (DE) | 2019-08-14 | — | — | EP | claimed |
| WO-2018065536-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | FREIE UNIVERSITÄT BERLIN (DE) | 2018-04-12 | — | — | WO | claimed |
| EP-3305783-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | Freie Universität Berlin (DE) | 2018-04-11 | — | — | EP | claimed |
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |
| US-7812040-B2 | such as 3-(3-Acetyl-phenyl)-1-[3-(3-chloro-4-pyrrolidin-1-ylmethyl-phenoxy)-cyclobutylmethyl]-1-methyl-urea, used for the treatment of , schizophrenia, Alzheimer's disease, attention-deficit hyperactivity disorder, hypotension, allergies, cardiovascular, gastrointestinal and psychological disorders | PFIZER INC. (US) | 2010-10-12 | — | — | US | claimed |
| US-20090131433-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 2009-05-21 | — | — | US | claimed |
| EP-1899296-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | Pfizer Products Incorporated (US) | 2008-03-19 | — | — | EP | claimed |
| WO-2006136924-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-12-28 | — | — | WO | claimed |
| CN-1043140-C | Chlorins, isobacteriochlorins, bacteriochlorins, and methods of making the compounds described herein from the beta, beta'-unsubstituted tetrapyrrole macrocycle | HOECHST AG (DE) | 1999-04-28 | — | — | CN | claimed |
| CN-1119013-A | Hydroxymethyl furazan carboxylic acid derivatives and their use in the treatment of cardiovascular disease | CASSELLA FARBWERKE MAINKUR AG (DE) | 1996-03-20 | — | — | CN | claimed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20250109137-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-03 | — | — | US | disclosed |
| EP-4522596-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-1043140-C | Chlorins, isobacteriochlorins, bacteriochlorins, and methods of making the compounds described herein from the beta, beta'-unsubstituted tetrapyrrole macrocycle | HOECHST AG (DE) | 1999-04-28 | — | — | CN | disclosed |
| CN-1119013-A | Hydroxymethyl furazan carboxylic acid derivatives and their use in the treatment of cardiovascular disease | CASSELLA FARBWERKE MAINKUR AG (DE) | 1996-03-20 | — | — | CN | disclosed |
| WO-1995019355-A1 | FURAZAN CARBOXYLIC ACID DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-20 | — | — | WO | disclosed |