SCHEMBL7767700

SCHEMBL7767700

O=C(O)c1cnc(C(=O)O)cn1.[CaH2]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.56
HCAR2 Q8TDS4 2/20 0.56
NAPRT Q6XQN6 2/20 0.56
P4HTM Q9NXG6 5/20 0.54
P4HA1 P13674 1/20 0.54
MIF P14174 1/20 0.54
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 3/20 0.48
ASPH Q12797 3/20 0.48
KDM8 Q8N371 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SIRT6 Q8N6T7 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.44
LMNA P02545 1/20 0.44
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ACMSD Q8TDX5 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70035 0.97 KDM4E (0.59) KDM4EHCAR2NAPRTP4HTMP4HA1
Iodide SCHEMBL6129698 0.94 KDM4E (0.52) KDM4EHCAR2NAPRTP4HTMP4HA1
Hydrochloric Acid SCHEMBL11594387 0.94 KDM4E (0.56) KDM4EHCAR2NAPRTP4HTMP4HA1
Water SCHEMBL28665454 0.94 KDM4E (0.56) KDM4EHCAR2NAPRTP4HTMP4HA1
Water SCHEMBL336347 0.94 KDM4E (0.56) KDM4EHCAR2NAPRTP4HTMP4HA1
Iodide SCHEMBL7459681 0.91 KDM4E (0.54) KDM4EHCAR2NAPRTP4HTMP4HA1
Water SCHEMBL6129699 0.88 KDM4E (0.52) KDM4EHCAR2NAPRTP4HTMP4HA1
SCHEMBL17712841 0.86 SIRT6 (0.64) KDM4EHCAR2NAPRTP4HTMP4HA1
SCHEMBL17725120 0.84 KDM4E (0.48) KDM4EHCAR2NAPRTP4HTMP4HA1
SCHEMBL15305157 0.84 KDM4E (0.48) KDM4EHCAR2NAPRTP4HTMP4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624813-B1 Light valve suspensions and films containing UV absorbers and light valves containing the same RESEARCH FRONTIERS INC (US) 2001-07-04 EP disclosed
EP-0669010-B1 LIGHT MODULATING FILM OF IMPROVED CLARITY FOR A LIGHT VALVE RESEARCH FRONTIERS INC (US) 2000-06-21 EP disclosed
EP-0989445-A2 A liquid suspension for a light valve RESEARCH FRONTIERS INCORPORATED (US) 2000-03-29 EP disclosed
US-5467217-A Light valve suspensions and films containing UV absorbers and light valves containing the same RESEARCH FRONTIERS INCORPORATED (US) 1995-11-14 US disclosed
US-5463492-A Light modulating film of improved clarity for a light valve RESEARCH FRONTIERS INCORPORATED (US) 1995-10-31 US disclosed
US-5463491-A Light valve employing a film comprising an encapsulated liquid suspension, and method of making such film RESEARCH FRONTIERS INCORPORATED (US) 1995-10-31 US disclosed
EP-0669010-A4 1995-09-27 EP disclosed
EP-0669010-A1 LIGHT MODULATING FILM OF IMPROVED CLARITY FOR A LIGHT VALVE RESEARCH FRONTIERS INCORPORATED (US) 1995-08-30 EP disclosed
EP-0624813-A1 Light valve suspensions and films containing UV absorbers and light valves containing the same RESEARCH FRONTIERS INCORPORATED (US) 1994-11-17 EP disclosed
WO-1994011772-A1 LIGHT MODULATING FILM OF IMPROVED CLARITY FOR A LIGHT VALVE RESEARCH FRONTIERS INCORPORATED (US) 1994-05-26 WO disclosed