Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.42 |
| ▸ | COMT | P21964 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2642010 | 0.93 | HTT (0.44) | FGFR1KMT2AHTTSRC | |
| SCHEMBL4352301 | 0.80 | HTT (0.58) | FGFR1HTTSRC | |
| SCHEMBL4015486 | 0.74 | HTT (0.71) | FGFR1KMT2AHTT | |
| SCHEMBL17185577 | 0.74 | F9 (0.47) | FGFR1F9F10SRC | |
| SCHEMBL12822351 | 0.72 | FGFR1 (0.64) | FGFR1F10HTT | |
| SCHEMBL31608474 | 0.71 | HTT (0.49) | F9F10HTT | |
| SCHEMBL12822182 | 0.71 | FGFR1 (0.80) | FGFR1SRC | |
| SCHEMBL2641937 | 0.71 | GABRP (0.46) | FGFR1KMT2AHTT | |
| SCHEMBL18226399 | 0.70 | FGFR1 (0.47) | FGFR1HTT | |
| SCHEMBL2659465 | 0.70 | FGFR1 (0.69) | FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |