Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL2642016 | 0.93 | FGFR1 (0.42) | HTTFGFR1KMT2ASRC | |
| SCHEMBL4352301 | 0.85 | HTT (0.58) | HTTFGFR1SRC | |
| SCHEMBL4015486 | 0.80 | HTT (0.71) | HTTFGFR1KMT2AKDR | |
| SCHEMBL31608474 | 0.77 | HTT (0.49) | HTTKDR | |
| SCHEMBL2641937 | 0.76 | GABRP (0.46) | HTTFGFR1KMT2A | |
| SCHEMBL18226399 | 0.76 | FGFR1 (0.47) | HTTFGFR1 | |
| SCHEMBL8329072 | 0.73 | CYP17A1 (0.59) | HTTFGFR1KMT2ASRC | |
| SCHEMBL29642847 | 0.72 | GABRA1 (0.49) | HTTFGFR1KDRSRC | |
| SCHEMBL17940732 | 0.72 | GABRA1 (0.49) | HTTFGFR1KDRSRC | |
| SCHEMBL13045092 | 0.72 | FGFR1 (0.57) | HTTFGFR1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |