SCHEMBL26420673

SCHEMBL26420673

O=Cc1ccc2c(c1)C=Cc1cc(Br)ccc1O2

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
AHR P35869 3/20 0.45
CA12 O43570 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2A6 P11509 2/20 0.39
PTGS2 P35354 2/20 0.35
ERN1 O75460 1/20 0.35
PTPN1 P18031 1/20 0.35
APP P05067 2/20 0.35
KDM4E B2RXH2 1/20 0.34
RAB9A P51151 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
ALDH1A3 P47895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30861905 1.00 ALDH1A1 (0.46) ALDH1A1AHRCA12CA2CA9
SCHEMBL22863710 0.89 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL26420636 0.82 AHR (0.64) ALDH1A1AHRCA12CA2CA9
SCHEMBL482685 0.75 AHR (0.60) ALDH1A1AHRCA12CA2CA9
SCHEMBL27434828 0.75 ALDH1A1 (0.52) ALDH1A1CA12CA2CA9HSD17B10
SCHEMBL19885494 0.73 AHR (0.63) ALDH1A1AHRCA12CA2CA9
SCHEMBL23775788 0.72 ALDH1A1 (0.59) ALDH1A1AHRHSD17B10TDP1CYP2A6
SCHEMBL27438938 0.72 AHR (0.50) ALDH1A1AHRCA12CA2CA9
SCHEMBL8886564 0.69 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL10843571 0.69 ALDH1A1 (0.43) ALDH1A1HSD17B10TDP1CYP2A6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-07-04 US disclosed
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-07-04 US disclosed
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, UBE2D3, MDM2 ALDH1A1 2249/4885AHR 720/4885CA12 2288/4885
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2389/4885AHR 955/4885CA12 2385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.