SCHEMBL27434828

SCHEMBL27434828

COc1ccc2c(c1)C=Cc1cc(C=O)ccc1O2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
CYP2A6 P11509 1/20 0.52
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
PTGER4 P35408 1/20 0.44
TSHR P16473 1/20 0.43
MAOB P27338 1/20 0.41
CA2 P00918 2/20 0.41
TDP1 Q9NUW8 3/20 0.40
TRIM24 O15164 2/20 0.40
TRIM33 Q9UPN9 2/20 0.40
ERN1 O75460 1/20 0.40
TYR P14679 1/20 0.40
AOX1 Q06278 1/20 0.40
HPGD P15428 1/20 0.40
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
AURKA O14965 1/20 0.39
DAPK3 O43293 1/20 0.39
STK17B O94768 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22863710 0.84 ALDH1A1 (0.50) ALDH1A1CYP2A6TSHRTDP1TRIM24
SCHEMBL30861905 0.75 ALDH1A1 (0.46) ALDH1A1CYP2A6CA12CA9MAOB
SCHEMBL26420673 0.75 ALDH1A1 (0.46) ALDH1A1CYP2A6CA12CA9MAOB
SCHEMBL9616603 0.73 ALDH1A1 (0.65) ALDH1A1CYP2A6PTGER4TSHRMAOB
SCHEMBL29577162 0.73 ALDH1A1 (0.65) ALDH1A1CYP2A6PTGER4TSHRMAOB
SCHEMBL271175 0.73 ALDH1A1 (0.65) ALDH1A1CYP2A6PTGER4TSHRMAOB
SCHEMBL11005986 0.73 ALDH1A1 (0.46) ALDH1A1CYP2A6PTGER4TSHRTDP1
Methane SCHEMBL28484734 0.72 ALDH1A1 (0.63) ALDH1A1CYP2A6PTGER4TSHRMAOB
Hydrochloric Acid SCHEMBL28903002 0.72 ALDH1A1 (0.63) ALDH1A1CYP2A6PTGER4TSHRMAOB
SCHEMBL11399464 0.72 ALDH1A1 (0.45) ALDH1A1CYP2A6CA12CA9PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2389/4885CYP2A6 1800/4885CA12 2385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.