Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.42 |
| ▸ | PRKCG | P05129 | 4/20 | 0.42 |
| ▸ | PRKCB | P05771 | 4/20 | 0.42 |
| ▸ | PRKCA | P17252 | 4/20 | 0.42 |
| ▸ | PRKCH | P24723 | 4/20 | 0.42 |
| ▸ | PRKCI | P41743 | 4/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PRKACA | P17612 | 3/20 | 0.42 |
| ▸ | PRKACG | P22612 | 3/20 | 0.42 |
| ▸ | PRKACB | P22694 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27788261 | 0.98 | TNF (0.45) | TNFTTRNAPRTCYP3A4PRKD3 | |
| SCHEMBL117745 | 0.86 | CYP3A4 (0.56) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29696494 | 0.86 | CYP3A4 (0.56) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL8670953 | 0.84 | LMNA (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Fluoride SCHEMBL28263329 | 0.84 | CYP3A4 (0.55) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Sulfuric Acid SCHEMBL29120407 | 0.84 | CYP3A4 (0.55) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL9477757 | 0.84 | LMNA (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL18019196 | 0.82 | CA2 (0.61) | TNFCYP3A4PRKD3PRKCGPRKCB | |
| SCHEMBL30002842 | 0.82 | TNF (0.46) | TNFCYP3A4PRKD3PRKCGPRKCB | |
| SCHEMBL3129943 | 0.82 | TNF (0.46) | TNFCYP3A4PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117907492-B | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117907492-A | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-114577920-B | Method for detecting fasudil hydrochloride and related substances thereof | 远大医药（中国）有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-113358759-B | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-114577920-A | Method for detecting fasudil hydrochloride and related substances thereof | 远大医药（中国）有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-113358759-A | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-117907492-B | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117907492-A | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023189799-A1 | SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023189803-A1 | RESIST UNDERLAYER FILM FORMING COMPOSITION | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| CN-114577920-B | Method for detecting fasudil hydrochloride and related substances thereof | 远大医药（中国）有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-113358759-B | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-113358759-B | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-114577920-A | Method for detecting fasudil hydrochloride and related substances thereof | 远大医药（中国）有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113358759-A | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113358759-A | Method for detecting related substances in fasudil hydrochloride starting material | 昆药集团股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-108593831-B | HPLC detection method of fasudil hydrochloride related substances | 山东新华制药股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-111153856-A | Preparation method of fasudil hydrochloride impurity with genotoxicity | 湖南增达生物科技有限公司 | 2020-05-15 | — | — | CN | disclosed |