Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870952 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL227216 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL10985842 | 0.78 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL29748950 | 0.77 | MAPT (0.58) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2925587 | 0.77 | MAPT (0.58) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL394991 | 0.77 | KIF11 (0.70) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL30406158 | 0.77 | MAPT (0.49) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL16842506 | 0.77 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL21091040 | 0.77 | MAPT (0.58) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL28825700 | 0.77 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635969-A | Process for the manufacture of crystalline forms of enzalutamide | 安斯泰来制药有限公司 | 2018-01-26 | — | — | CN | disclosed |