Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | IDH2 | P48735 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748950 | 1.00 | MAPT (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4093215 | 0.92 | MAPT (0.51) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL20320380 | 0.87 | IDH2 (0.57) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL5508209 | 0.87 | MAPT (0.51) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL394991 | 0.86 | KIF11 (0.70) | MAPTALDH1A1GAANPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL28200105 | 0.86 | MAPT (0.50) | MAPTALDH1A1GAANPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL3601015 | 0.86 | MAPT (0.50) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL10985182 | 0.85 | MAPT (0.70) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL5261069 | 0.84 | MAPT (0.56) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL4088560 | 0.84 | MAPT (0.54) | MAPTALDH1A1GAANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772436-B2 | Process for producing 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl | AIR WATER INC. (JP) | 2010-08-10 | — | — | US | claimed |
| EP-1816118-B1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | AIR WATER INC (JP) | 2010-01-27 | — | — | EP | claimed |
| US-20090069602-A1 | Process for Producing 2,2'-Bis(Trifluoromethyl)-4,4'-Diaminobiphenyl | AIR WATER INC. (JP) | 2009-03-12 | — | — | US | claimed |
| EP-1816118-A1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | Air Water Inc. (JP) | 2007-08-08 | — | — | EP | claimed |
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | SEIKA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | SEIKA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| WO-2021131549-A1 | METHOD FOR PRODUCING DIAMINOBIPHENYL COMPOUND | セイカ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021131549-A1 | METHOD FOR PRODUCING DIAMINOBIPHENYL COMPOUND | セイカ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| US-7772436-B2 | Process for producing 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl | AIR WATER INC. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-7772436-B2 | Process for producing 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl | AIR WATER INC. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1816118-B1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | AIR WATER INC (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-20090069602-A1 | Process for Producing 2,2'-Bis(Trifluoromethyl)-4,4'-Diaminobiphenyl | AIR WATER INC. (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-1816118-A1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | Air Water Inc. (JP) | 2007-08-08 | — | — | EP | disclosed |
| EP-1816118-A1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | Air Water Inc. (JP) | 2007-08-08 | — | — | EP | disclosed |
| JP-2006265129-A | METHOD FOR PRODUCING 3,3'-BIS(TRIFLUOROMETHYL)HYDRAZOBENZENE | AIR WATER INC | 2006-10-05 | — | — | JP | disclosed |
| JP-2006143703-A | PRODUCTION METHOD OF 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | AIR WATER CHEMICAL INC | 2006-06-08 | — | — | JP | disclosed |
| WO-2006048935-A1 | PROCESS FOR PRODUCING 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | AIR WATER INC. (JP) | 2006-05-11 | — | — | WO | disclosed |
| US-5652239-A | TREATMENT OF STROKES, ISCHEMIC ATTACK, ANTAGONISTS OF EXCITATORY AMINO ACIDS GLUTAMATE AND ASPARTATE | IMPERIAL CHEMICAL COMPANY (GB) | 1997-07-29 | — | — | US | disclosed |
| EP-0512817-B1 | Pyridazinedione derivatives, their preparation and pharmaceutical applications | ZENECA LTD (GB) | 1997-02-19 | — | — | EP | disclosed |
| EP-0512817-A1 | Pyridazinedione derivatives, their preparation and pharmaceutical applications | ZENECA LIMITED (GB) | 1992-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402858-A1 | METHOD FOR PREPARING DIAMINOBIPHENYL COMPOUND | TERT, NT5C, DDC | MAPT 3209/4885ALDH1A1 1868/4885GAA 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.