SCHEMBL26422848

SCHEMBL26422848

CC(C)(C)c1ccccc1NC1CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
GAA P10253 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 1/20 0.43
SIGMAR1 Q99720 2/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
SCD O00767 1/20 0.40
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
ALOX12 P18054 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514285 0.92 LMNA (0.59) LMNAGAAKDM4EMAPTSIGMAR1
SCHEMBL25039341 0.91 LMNA (0.44) LMNAGAAKDM4EMAPTSIGMAR1
SCHEMBL15163867 0.88 LMNA (0.44) LMNAGAAKDM4EMAPTSIGMAR1
SCHEMBL82951 0.88 BRD4 (0.47) LMNAGAAKDM4EMAPTKMT2A
Hydrochloric Acid SCHEMBL69480 0.86 BRD4 (0.46) LMNAGAAKDM4EMAPTKMT2A
SCHEMBL3105796 0.83 LMNA (0.47) LMNAGAAKDM4ESIGMAR1GRIN2D
SCHEMBL2724849 0.80 SCD (0.56) GAAKDM4EMAPTSCDPOLB
SCHEMBL25011530 0.79 GAA (0.47) GAAKDM4ETHRBALDH1A1TDP1
SCHEMBL25009540 0.79 P2RY1 (0.40) LMNAGAAKDM4EMAPTSCD
SCHEMBL2637754 0.79 SCD (0.43) LMNAKDM4ESCDALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129040-A1 IMMUNOMODULATING AZALIDES ZOETIS SERVICES LLC 2023-04-27 US disclosed
US-20230129040-A1 IMMUNOMODULATING AZALIDES ZOETIS SERVICES LLC 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129040-A1 IMMUNOMODULATING AZALIDES IL2, MALT1, FCGRT LMNA 4875/4885GAA 3406/4885KDM4E 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.