SCHEMBL2642299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2642216	0.87	MAPT (0.44)	GCKMAPTGRM1EGFRLCK
	SCHEMBL2642274	0.87	GCK (0.41)	GCKMAPTGRM1EGFRERBB2
	SCHEMBL2643951	0.85	GCK (0.41)	GCKMAPTGRM1EGFRLCK
	SCHEMBL17300151	0.77	GCK (0.52)	GCKMAPTGRM1EGFRLCK
	SCHEMBL14667251	0.73	GCK (0.48)	GCKMAPTGRM1EGFRLCK
	SCHEMBL2642860	0.73	NPC1 (0.50)	GCKMAPTGRM1EGFR
	SCHEMBL2642232	0.72	MAPT (0.42)	GCKMAPTGRM1EGFRHDAC3
	SCHEMBL17300137	0.72	GCK (0.47)	GCKMAPTGRM1EGFRLCK
	SCHEMBL2660770	0.71	POLB (0.44)	GCKMAPTGRM1EGFRERBB2
	SCHEMBL17300146	0.71	GCK (0.47)	GCKMAPTGRM1EGFRLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.