SCHEMBL26423404

SCHEMBL26423404

c1cnc2oc3cc4cncnc4cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
EGFR P00533 9/20 0.38
TDO2 P48775 2/20 0.36
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
IMPDH2 P12268 1/20 0.34
GRM4 Q14833 1/20 0.33
FGFR4 P22455 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26423380 0.94 ALDH1A1 (0.41) ALDH1A1KDM4EEGFRTDO2PIK3CD
SCHEMBL26423441 0.83 EGFR (0.39) EGFRTDO2PIK3CDPIK3CAIMPDH2
SCHEMBL26423239 0.83 ALDH1A1 (0.46) ALDH1A1KDM4EGRM4
SCHEMBL26423348 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EEGFRPIK3CDPIK3CA
SCHEMBL26423242 0.81 KDM4E (0.44) ALDH1A1KDM4EGRM4
SCHEMBL19758249 0.81 AHR (0.45) ALDH1A1KDM4EEGFRTDO2PIK3CD
SCHEMBL26423245 0.81 KDM4E (0.44) ALDH1A1KDM4EGRM4
SCHEMBL26423401 0.80 EGFR (0.38) KDM4EEGFRTDO2PIK3CDPIK3CA
SCHEMBL26423400 0.79 EGFR (0.36) EGFRPIK3CDPIK3CAIMPDH2FGFR4
SCHEMBL26423507 0.78 KDM4E (0.36) ALDH1A1KDM4EEGFRTDO2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL OCIAD2, OCIAD1, AZI2 ALDH1A1 302/4885KDM4E 2800/4885EGFR 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.