SCHEMBL26423239

SCHEMBL26423239

c1cnc2cc3c(cc2c1)oc1ncccc13

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 3/20 0.46
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
NPC1 O15118 2/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
CYP3A4 P08684 1/20 0.41
CASP6 P55212 1/20 0.40
CASP1 P29466 2/20 0.40
HTT P42858 2/20 0.40
MAPT P10636 2/20 0.40
CYP1A2 P05177 2/20 0.40
MEN1 O00255 1/20 0.40
CASP7 P55210 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2C19 P33261 1/20 0.40
NR4A2 P43354 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26423246 0.93 ALDH1A1 (0.46) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL26423368 0.86 ALDH1A1 (0.49) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL26423221 0.86 ALDH1A1 (0.53) ALDH1A1KDM4ENPC1CYP3A4MAPT
SCHEMBL26423212 0.83 MAPT (0.49) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL26423348 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL26423404 0.83 ALDH1A1 (0.41) ALDH1A1KDM4EGRM4
SCHEMBL24910796 0.78 CASP6 (0.50) ALDH1A1PDGFRBPDGFRANPC1POLB
SCHEMBL24910926 0.78 ALDH1A1 (0.42) ALDH1A1KDM4ENPC1RAB9ACYP3A4
SCHEMBL26423225 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL26423242 0.78 KDM4E (0.44) ALDH1A1KDM4ENPC1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL OCIAD2, OCIAD1, AZI2 ALDH1A1 302/4885KDM4E 2800/4885PDGFRB 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.