Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398830 | 0.84 | TAAR1 (0.59) | TAAR1LPLLIPGPGRMAPT | |
| SCHEMBL15519549 | 0.81 | TAAR1 (0.61) | TAAR1HDAC2LPLLIPGPGR | |
| SCHEMBL24359523 | 0.76 | TDP1 (0.32) | HDAC2MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30468965 | 0.76 | TDP1 (0.32) | HDAC2MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL613358 | 0.74 | CYP3A4 (0.48) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL6366825 | 0.73 | MAOA (0.47) | MAPTMEN1KMT2ATDP1HTR2C | |
| SCHEMBL30398364 | 0.73 | MAOA (0.47) | MAPTMEN1KMT2ATDP1HTR2C | |
| SCHEMBL394300 | 0.72 | TAAR1 (0.76) | TAAR1LPLLIPGPGRMAPT | |
| SCHEMBL1161258 | 0.70 | TAAR1 (1.00) | TAAR1LPLLIPGMAPTHSD17B10 | |
| SCHEMBL7869707 | 0.70 | CYP3A4 (0.67) | MAPTMEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191533-A1 | THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR | 고려대학교 산학협력단 | 2023-10-05 | — | — | WO | disclosed |