Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26423723 | 0.88 | CYP2A6 (0.33) | CYP2A6KDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL26423715 | 0.79 | CYP2A6 (0.33) | CYP2A6KDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL26423747 | 0.78 | LATS1 (0.33) | CYP2A6KDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL26423722 | 0.78 | CDK5 (0.33) | CYP2A6KDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL26423697 | 0.75 | MAPK14 (0.38) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL26423605 | 0.74 | ALDH1A1 (0.38) | CYP2A6KDM4EALDH1A1HTTNCOA1 | |
| SCHEMBL26423708 | 0.73 | LIMK1 (0.40) | CYP2A6KDM4ELIMK1PIK3CACLK1 | |
| SCHEMBL26423491 | 0.73 | TDO2 (0.33) | CDK5CLK1CDK5R1 | |
| SCHEMBL26423721 | 0.72 | LIMK1 (0.40) | KDM4EALDH1A1HTTLIMK1PIK3CG | |
| SCHEMBL26423500 | 0.71 | CLK1 (0.31) | DYRK1ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | OCIAD2, OCIAD1, AZI2 | CYP2A6 1228/4885KDM4E 2800/4885ALDH1A1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.