SCHEMBL2642473

SCHEMBL2642473

O=C(O)Cc1nn[c]s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970396 0.74 SMN1; SMN2 (0.47)
SCHEMBL11052382 0.66 TSHR (0.36)
SCHEMBL8626191 0.64 POLB (0.34)
SCHEMBL11035427 0.62
SCHEMBL10403239 0.61 F2 (0.39)
SCHEMBL11243212 0.61
SCHEMBL1686855 0.61 F2 (0.70)
SCHEMBL9662773 0.61 F2 (0.39)
SCHEMBL10403237 0.61 F2 (0.39)
SCHEMBL5545037 0.61 SMN1; SMN2 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4385178-A REACTION OF A CEPHALOSPORANIC ACID WITH A THIOL COMPOUND IN THE PRESENCE OF BORON TRIFLUORIDE TOYAMA CHEMICAL CO., LTD. (JP) 1983-05-24 US claimed
US-4317907-A ANHYDROUS CONDITIONS IN THE PRESENCE OF BOREN TRIFLUORIDE OR ONE OF ITS COMPLEXES TOYAMA CHEMICAL CO., LTD. (JP) 1982-03-02 US claimed
US-4201781-A BACTERICIDES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1980-05-06 US claimed
EP-1496052-B1 NOVEL AMINOBENZAMIDE DERIVATIVE BANYU PHARMA CO LTD (JP) 2009-08-05 EP disclosed
US-7253188-B2 Aminobenzamide derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-07 US disclosed
US-20050282815-A1 Novel aminobenzamide derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-12-22 US disclosed
EP-1496052-A1 NOVEL AMINOBENZAMIDE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-01-12 EP disclosed
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
US-5089490-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4758556-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 US disclosed
US-4729990-A PENICILLIN FARMITALIA CARLO ERBA S.P.A. (IT) 1988-03-08 US disclosed
US-4577016-A DISPLACEMENT FARMITALIA CARLO ERBA S.P.A. (IT) 1986-03-18 US disclosed
US-4399131-A Cephem derivatives HOECHST AG (DE) 1983-08-16 US disclosed
US-4385181-A CHAMICAL INTERMEDIATES FOR CEPHALOSPORINS RHONE POULENC INDUSTRIES (FR) 1983-05-24 US disclosed
US-4307116-A BACTERICIDES RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
US-4203982-A Arylmalonamidomethoxycephalosporins SHIONOGI & CO., LTD. (JP) 1980-05-20 US disclosed
US-4201781-A BACTERICIDES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1980-05-06 US disclosed
US-4201781-A BACTERICIDES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1980-05-06 US disclosed