Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | IRS1 | P35568 | 1/20 | 0.33 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769560 | 0.81 | F2 (0.62) | F2HTTHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL10404082 | 0.76 | F2 (0.39) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL1686855 | 0.74 | F2 (0.70) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL2705929 | 0.74 | GLS (0.45) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL10403239 | 0.74 | F2 (0.39) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL5545037 | 0.74 | SMN1; SMN2 (0.56) | F2HTTHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL9662773 | 0.74 | F2 (0.39) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL9662768 | 0.74 | F2 (0.36) | F2HTTHSD17B10GLSALDH1A1 | |
| SCHEMBL9478953 | 0.69 | L3MBTL1 (0.41) | F2HTTHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL5515009 | 0.69 | LMNA (0.40) | F2HTTHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| EP-0070803-A2 | Antibiotically active aminotriazolylcephalosporin derivatives and their preparation | CIBA-GEIGY AG (CH) | 1983-01-26 | — | — | EP | disclosed |
| US-4271296-A | CEPHALOSPORINS AND DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4271295-A | HALOGENATION STEP | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4233216-A | INTERMEDIATES FOR OXADETHIACEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1980-11-11 | — | — | US | disclosed |
| US-4220766-A | FROM PENICILLINS | SHIONOGI & CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |