SCHEMBL26426327

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL857284	0.84	HTT (0.55)	KCNQ4KCNQ5CYP17A1HTTLMNA
	SCHEMBL15614546	0.84	MAPT (0.51)	KCNQ4KCNQ5CYP17A1RXFP1HTT
	SCHEMBL5800267	0.83	KCNQ4 (0.51)	KCNQ4KCNQ5CYP17A1RXFP1HTT
	SCHEMBL8292291	0.83	KCNQ4 (0.48)	KCNQ4KCNQ5CYP17A1HTTLMNA
	SCHEMBL27398698	0.83	MAPT (0.51)	KCNQ4KCNQ5RXFP1HPGDHTT
	SCHEMBL21251511	0.82	KCNQ4 (0.48)	KCNQ4KCNQ5CYP17A1RXFP1HPGD
	SCHEMBL23954504	0.82	KMT2A (0.47)	KCNQ4KCNQ5HPGDGAAMEN1
	SCHEMBL197145	0.82	HDAC1 (0.55)	KCNQ4KCNQ5CYP17A1HTT
	SCHEMBL22092641	0.82	KCNQ4 (0.47)	KCNQ4KCNQ5CYP17A1RXFP1HTT
	SCHEMBL29581478	0.82	HDAC1 (0.55)	KCNQ4KCNQ5CYP17A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.