Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3673318 | 0.97 | BLM (0.64) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL224548 | 0.90 | TAAR1 (0.72) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3668004 | 0.87 | BLM (0.74) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3168355 | 0.87 | BLM (0.74) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| Iodide SCHEMBL29101247 | 0.87 | TAAR1 (0.68) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| Phenethylamine SCHEMBL9084593 | 0.86 | TAAR1 (0.84) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL27238704 | 0.83 | HRH3 (0.79) | LOXL2TAAR1HRH3ABAT | |
| SCHEMBL15828 | 0.83 | HRH3 (0.79) | LOXL2TAAR1HRH3ABAT | |
| SCHEMBL6314062 | 0.82 | MAOA (0.54) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 | |
| SCHEMBL143553 | 0.81 | GFER (0.77) | LOXL2TAAR1HTR2ACYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265033-A | Certain diarylimidaozle derivatives, new class of NPY speific ligands | NEUROGEN CORP (US) | 2000-08-30 | — | — | CN | claimed |
| CN-117580889-A | Curing agent for epoxy resins | SIKA技术股份公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023114125-A1 | DETECTION DEVICE AND METHODS OF USE THEREOF | AMULET, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20200332193-A1 | LIQUID CRYSTAL ELEMENT USED FOR PHASE CONTROL OF ELECTROMAGNETIC WAVE SIGNAL | JNC CORPORATION (JP) | 2020-10-22 | — | — | US | disclosed |
| US-20170275236-A1 | DIAMINE COMPOUNDS, DINITRO COMPOUNDS AND OTHER COMPOUNDS, AND METHODS OF PRODUCING THEREOF AND USES RELATED THEREOF | MICROMIDAS, INC. (US) | 2017-09-28 | — | — | US | disclosed |
| US-9611273-B2 | Trioxane thioacetal monomers and dimers and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-04-04 | — | — | US | disclosed |
| EP-2943483-B1 | BENZYLAMINE DERIVATIVES | KALVISTA PHARMACEUTICALS LTD (GB) | 2017-03-01 | — | — | EP | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| CN-101128470-A | Novel compounds | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |
| CN-101119980-A | Novel benzothiazole carboxamides | ASTRAZENECA AB (SE) | 2008-02-06 | — | — | CN | disclosed |
| WO-2007150046-A2 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS VIA MODULATION OF MEGALIN ACTIVITY | SIRION THERAPEUTICS, INC (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6890930-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| CN-1346350-A | Compounds that inhibit VLA-4 mediated leukocyte adhesion | ELAN PHARM INC (US) | 2002-04-24 | — | — | CN | disclosed |
| CN-1280561-A | Amidocarboxylic acid derivatives | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| CN-1265033-A | Certain diarylimidaozle derivatives, new class of NPY speific ligands | NEUROGEN CORP (US) | 2000-08-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | LOXL2 3170/4885TAAR1 141/4885HTR2A 56/4885 |
| US-20170275236-A1 | DIAMINE COMPOUNDS, DINITRO COMPOUNDS AND OTHER COMPOUNDS, AND METHODS OF PRODUCING THEREOF AND USES RELATED THEREOF | DDC, DDT, DAO | LOXL2 2299/4885TAAR1 833/4885HTR2A 1665/4885 |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | LOXL2 2232/4885TAAR1 4223/4885HTR2A 2997/4885 |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | GCKR, GCK, HK2 | LOXL2 2252/4885TAAR1 4214/4885HTR2A 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.