SCHEMBL26429142

SCHEMBL26429142

C=NC(=O)[C@@H]1CCCN1C(=O)CCc1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.47
POLB P06746 1/20 0.44
HTR1A P08908 3/20 0.44
HTR7 P34969 3/20 0.44
TACR1 P25103 1/20 0.41
CASP3 P42574 1/20 0.40
CASP7 P55210 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
S100A4 P26447 1/20 0.39
PRCP P42785 1/20 0.39
ACE P12821 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26426189 0.91 HTR1A (0.46) F2POLBHTR1AHTR7TACR1
SCHEMBL26429166 0.86 F2 (0.48) F2HTR1AHTR7
SCHEMBL26418988 0.84 PREP (0.45) F2
SCHEMBL26429177 0.83 F2 (0.58) F2POLBACE
SCHEMBL26429154 0.81 F2 (0.53) F2POLBPRCP
SCHEMBL26424878 0.81 F2 (0.48) F2
SCHEMBL26428633 0.81 F2 (0.64) F2HTR1AHTR7TAAR1ACE
SCHEMBL26426169 0.80 F2 (0.52) F2HTR1AHTR7PRCPACE
SCHEMBL26427890 0.80 DPP4 (0.44) F2HTR1AHTR7ACE
SCHEMBL26428651 0.79 FAP (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed