Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26321836 | 1.00 | ACHE (0.54) | ACHEALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL26430183 | 1.00 | ACHE (0.54) | ACHEALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL17894162 | 0.91 | AOC3 (0.44) | ACHEALDH1A1AOC3DRD2DRD4 | |
| SCHEMBL19435369 | 0.91 | AOC3 (0.44) | ACHEALDH1A1AOC3DRD2DRD4 | |
| SCHEMBL26430723 | 0.91 | AOC3 (0.44) | ACHEALDH1A1AOC3DRD2DRD4 | |
| SCHEMBL15617670 | 0.89 | CHRNA7 (0.42) | ACHEALDH1A1LMNATDP1NFE2L2 | |
| SCHEMBL12789806 | 0.83 | ACHE (0.59) | ACHEALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL15617630 | 0.81 | LMNA (0.46) | ACHEALDH1A1LMNASMN1; SMN2NFE2L2 | |
| SCHEMBL21831189 | 0.80 | ACHE (0.62) | ACHEALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL30211236 | 0.80 | USP2 (0.41) | ALDH1A1AOC3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CORTEVA AGRISCIENCE LLC (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CYP51A1, CYP4X1, CYP4F3 | ACHE 387/4885ALDH1A1 3446/4885LMNA 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.