Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26430157 | 1.00 | ACHE (0.52) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL21914829 | 0.92 | CYP3A4 (0.47) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL21914753 | 0.92 | CYP3A4 (0.47) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL19765292 | 0.92 | CYP3A4 (0.47) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL9204391 | 0.89 | TSHR (0.46) | ACHEKMT2ACYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9204405 | 0.89 | TSHR (0.46) | ACHEKMT2ACYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL26430192 | 0.82 | ACHE (0.50) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL26430093 | 0.82 | ACHE (0.50) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL26430122 | 0.82 | ACHE (0.50) | ACHELMNACYP3A4KMT2ACYP2D6 | |
| SCHEMBL19448772 | 0.79 | CYP3A4 (0.56) | ACHELMNACYP3A4KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CORTEVA AGRISCIENCE LLC (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639334-B2 | Methods for synthesis of oxypicolinamides | CYP51A1, CYP4X1, CYP4F3 | ACHE 387/4885LMNA 4463/4885CYP3A4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.