Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19765292 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL21914753 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL21914829 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL13539404 | 0.80 | CYP3A4 (0.44) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL23003766 | 0.80 | CYP3A4 (0.44) | CYP3A4CYP17A1RAB9AUSP2KCNN4 | |
| SCHEMBL26430216 | 0.79 | ACHE (0.52) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL7430311 | 0.79 | CYP3A4 (0.43) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL26430157 | 0.79 | ACHE (0.52) | CYP3A4CYP17A1RAB9AUSP2CYP19A1 | |
| SCHEMBL19448778 | 0.76 | CYP3A4 (0.39) | CYP3A4CYP17A1CYP19A1CYP2D6CYP2C19 | |
| SCHEMBL6470482 | 0.75 | CYP2C19 (0.55) | CYP3A4CYP17A1KCNN4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | CYP3A4 101/4885CYP17A1 196/4885RAB9A 3281/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | CYP3A4 140/4885CYP17A1 217/4885RAB9A 3315/4885 |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | CYP3A4 101/4885CYP17A1 196/4885RAB9A 3281/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | CYP3A4 101/4885CYP17A1 196/4885RAB9A 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.