Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927192 | 0.87 | PTGER4 (0.38) | TAF1CECR2BRD9KMT2ACD38 | |
| SCHEMBL21506647 | 0.87 | P2RX7 (0.39) | TAF1CECR2BRD9KMT2AP2RX7 | |
| SCHEMBL22927186 | 0.86 | TAF1 (0.37) | TAF1CECR2BRD9KMT2ACD38 | |
| SCHEMBL26432865 | 0.80 | PBK (0.39) | TAF1CECR2BRD9CD38HSD17B10 | |
| SCHEMBL26432977 | 0.80 | L3MBTL1 (0.36) | KMT2AL3MBTL1EZH2TAS1R3TAS1R1 | |
| SCHEMBL26432948 | 0.80 | CD38 (0.42) | TAF1CECR2BRD9KMT2ACD38 | |
| SCHEMBL26432855 | 0.80 | KMT2A (0.47) | KMT2ACD38 | |
| SCHEMBL21481820 | 0.77 | TAF1 (0.42) | TAF1CECR2BRD9CD38P2RX7 | |
| SCHEMBL21506731 | 0.77 | TAF1 (0.42) | TAF1CECR2BRD9CD38P2RX7 | |
| SCHEMBL26432962 | 0.77 | CD38 (0.41) | KMT2ACD38HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638704-B2 | Bicyclic compounds and their use in the treatment of cancer | TEMPEST THERAPEUTICS, INC. (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638704-B2 | Bicyclic compounds and their use in the treatment of cancer | PTGER4, PTGER1, PTGER3 | TAF1 2351/4885CECR2 3166/4885BRD9 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.