Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437401 | 0.84 | KMT2A (0.50) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL3878195 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL22930093 | 0.79 | LMNA (0.36) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL30227819 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL30227887 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL10700633 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL1697 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL143772 | 0.78 | MEN1 (0.61) | ALDH1A1LMNAKMT2AL3MBTL1SLC6A2 | |
| SCHEMBL2643016 | 0.77 | LMNA (0.42) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL1324825 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAKMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496052-B1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20050282815-A1 | Novel aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-12-22 | — | — | US | disclosed |
| EP-1496052-A1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282815-A1 | Novel aminobenzamide derivative | GCKR, GCK, HK2 | ALDH1A1 1496/4885LMNA 4275/4885KMT2A 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.