Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.73 |
| ▸ | IL1B | P01584 | 11/20 | 0.61 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168047 | 1.00 | NLRP3 (0.73) | NLRP3IL1BKAT2BALDH1A1 | |
| SCHEMBL24840758 | 1.00 | NLRP3 (0.73) | NLRP3IL1BKAT2BALDH1A1 | |
| SCHEMBL26438084 | 0.91 | NLRP3 (0.66) | NLRP3IL1BKAT2B | |
| SCHEMBL26435049 | 0.91 | NLRP3 (0.66) | NLRP3IL1BKAT2B | |
| SCHEMBL29275788 | 0.89 | NLRP3 (0.61) | NLRP3IL1B | |
| SCHEMBL26436139 | 0.89 | IL1B (0.79) | NLRP3IL1B | |
| SCHEMBL30213939 | 0.89 | NLRP3 (0.61) | NLRP3IL1B | |
| SCHEMBL30994383 | 0.88 | NLRP3 (0.67) | NLRP3IL1BKAT2BALDH1A1 | |
| SCHEMBL29275801 | 0.88 | NLRP3 (0.67) | NLRP3IL1BKAT2BALDH1A1 | |
| SCHEMBL26435319 | 0.88 | NLRP3 (0.60) | NLRP3IL1BKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881401-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |