Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.68 |
| ▸ | GIPR | P48546 | 13/20 | 0.68 |
| ▸ | GLP1R | P43220 | 4/20 | 0.68 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244419 | 0.96 | GCGR (0.64) | GCGRGIPRGLP1RMCHR1POLB | |
| SCHEMBL2643165 | 0.89 | GCGR (0.71) | GCGRGIPRGLP1RMCHR1POLB | |
| SCHEMBL2647064 | 0.87 | GCGR (0.77) | GCGRGIPRGLP1RMCHR1POLB | |
| SCHEMBL2643544 | 0.86 | GCGR (0.63) | GCGRGIPRGLP1RMCHR1THRB | |
| SCHEMBL2643547 | 0.86 | GCGR (0.63) | GCGRGIPRGLP1RMCHR1THRB | |
| SCHEMBL2643524 | 0.86 | GCGR (0.70) | GCGRGIPRGLP1RMCHR1THRB | |
| SCHEMBL2643526 | 0.86 | GCGR (0.70) | GCGRGIPRGLP1RMCHR1THRB | |
| SCHEMBL2643362 | 0.85 | GCGR (0.75) | GCGRGIPRGLP1RMCHR1POLB | |
| SCHEMBL2655795 | 0.81 | GCGR (1.00) | GCGRGIPRGLP1R | |
| SCHEMBL2652197 | 0.81 | GCGR (1.00) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509509-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2005-03-02 | — | — | EP | disclosed |
| US-20040116483-A1 | Glucagon antagonists/inverse agonists | BEHRENS CARSTEN (DK) | 2004-06-17 | — | — | US | disclosed |
| WO-2003097619-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2003-11-27 | — | — | WO | disclosed |
| US-6649641-B2 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-11-18 | — | — | US | disclosed |
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-10-30 | — | — | US | disclosed |
| EP-1345890-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | Novo Nordisk A/S (DK) | 2003-09-24 | — | — | EP | disclosed |
| US-20020187982-A1 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2002-12-12 | — | — | US | disclosed |
| WO-2002040445-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187982-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | GCGR 3/4885GIPR 4/4885GLP1R 1/4885 |
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | GCGR 3/4885GIPR 4/4885GLP1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.