Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | COMT | P21964 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436031 | 0.92 | NLRP3 (0.44) | NLRP3COMTKMT2AMEN1TDP1 | |
| SCHEMBL26435872 | 0.87 | IL1B (0.39) | NLRP3KMT2AMEN1TDP1MAPT | |
| SCHEMBL26435079 | 0.85 | NLRP3 (0.50) | NLRP3KMT2AMAPTKDM4EHTT | |
| SCHEMBL26435325 | 0.85 | NLRP3 (0.37) | NLRP3KMT2AMEN1TDP1MAPT | |
| SCHEMBL26435361 | 0.85 | NLRP3 (0.46) | NLRP3COMTKMT2AMEN1TDP1 | |
| SCHEMBL26435695 | 0.85 | NLRP3 (0.46) | NLRP3COMTKDM4ECHEK2L3MBTL1 | |
| SCHEMBL26435356 | 0.82 | NLRP3 (0.52) | NLRP3COMTKMT2AMEN1TDP1 | |
| SCHEMBL29275814 | 0.81 | NLRP3 (0.69) | NLRP3KAT2BIL1B | |
| SCHEMBL30108645 | 0.81 | NLRP3 (0.69) | NLRP3KAT2BIL1B | |
| SCHEMBL26435350 | 0.81 | NLRP3 (0.69) | NLRP3KAT2BIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |