Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.55 |
| ▸ | KDM4A | O75164 | 4/20 | 0.52 |
| ▸ | KDM4B | O94953 | 4/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 2/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24919461 | 0.84 | ADORA3 (0.62) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417847 | 0.82 | ADORA3 (0.66) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417908 | 0.80 | ADORA3 (0.51) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL15173226 | 0.78 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL29616747 | 0.78 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL24918932 | 0.78 | ADORA3 (0.61) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23418017 | 0.78 | ADORA3 (0.55) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL26421519 | 0.78 | ADORA3 (0.52) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417740 | 0.78 | ADORA3 (0.56) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417815 | 0.78 | ADORA3 (0.56) | ADORA3KDM4AKDM4BKDM5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | ADORA3 4024/4885KDM4A 656/4885KDM4B 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.