SCHEMBL26435474

SCHEMBL26435474

c1cc(-c2nc(-c3ccc4c(c3)oc3ccccc34)nc(-c3cccc4c3sc3ccccc34)n2)cc(-c2cccc3ccc4ccccc4c23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 8/20 0.42
ALOX5 P09917 2/20 0.41
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
HCRTR1 O43613 1/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
DUSP3 P51452 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435475 0.94 ALOX5 (0.41) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26435487 0.91 ALOX5 (0.38) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL21261128 0.90 PRKDC (0.47) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26435530 0.89 ALOX5 (0.42) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26435627 0.89 ALOX5 (0.40) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26435701 0.89 ALOX5 (0.39) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26047837 0.89 PRKDC (0.43) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL21261131 0.88 PRKDC (0.47) PRKDCALOX5PIK3CDPIK3CBHCRTR1
SCHEMBL27361604 0.88 PRKDC (0.41) PRKDCALOX5TDP1L3MBTL1PIK3CD
SCHEMBL26047536 0.88 PRKDC (0.43) PRKDCALOX5TDP1L3MBTL1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 PRKDC 3142/4885ALOX5 1266/4885TDP1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.