SCHEMBL26435552

SCHEMBL26435552

c1ccc(-c2ccc3c4ccccc4n(-c4ccc(-c5nc(-c6cccc(-c7cccc8ccc9ccccc9c78)c6)nc(-c6cccc7c6oc6ccccc67)n5)cc4)c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
PRKDC P78527 1/20 0.33
GGPS1 O95749 1/20 0.31
MAPT P10636 2/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
PIM1 P11309 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435056 0.96 ALOX5 (0.35) ALOX5PRKDCGGPS1MAPTSIRT2
SCHEMBL26435709 0.94 ALOX5 (0.36) ALOX5PRKDCMAPTSIRT2SIRT1
SCHEMBL26435569 0.93 ALOX5 (0.37) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL26435050 0.93 ALOX5 (0.36) ALOX5PRKDCMAPTSIRT2SIRT1
SCHEMBL26434991 0.91 ALOX5 (0.37) ALOX5PRKDCSIRT2SIRT1KDM4E
SCHEMBL26435054 0.91 ALOX5 (0.34) ALOX5PRKDCSIRT2SIRT1PIM1
SCHEMBL26435652 0.91 ALOX5 (0.38) ALOX5PRKDCGGPS1MAPTSIRT2
SCHEMBL26435559 0.91 ALOX5 (0.38) ALOX5PRKDCGGPS1SIRT2SIRT1
SCHEMBL24303275 0.90 ALOX5 (0.44) ALOX5PRKDCGGPS1MAPTPIM1
SCHEMBL18505428 0.90 ALOX5 (0.44) ALOX5PRKDCGGPS1MAPTPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 ALOX5 1266/4885PRKDC 3142/4885GGPS1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.