SCHEMBL26435616

SCHEMBL26435616

c1ccc(-n2c3ccccc3c3cccc(-c4nc(-c5cccc(-c6cccc7ccc8ccccc8c67)c5)nc(-c5cccc6c5oc5ccccc56)n4)c32)cc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
GGPS1 O95749 1/20 0.32
PRKDC P78527 2/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ABCG2 Q9UNQ0 2/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAPK3 P27361 1/20 0.30
AHR P35869 1/20 0.30
PAX8 Q06710 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435114 0.92 SIRT2 (0.35) ALOX5SIRT2SIRT1PRKDCPIK3CD
SCHEMBL26435615 0.91 ALOX5 (0.36) ALOX5SIRT2SIRT1GGPS1PRKDC
SCHEMBL26435652 0.90 ALOX5 (0.38) ALOX5SIRT2SIRT1GGPS1PRKDC
SCHEMBL26435567 0.90 ALOX5 (0.39) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24352204 0.90 ALOX5 (0.43) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL16811057 0.90 ALOX5 (0.38) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24352643 0.89 ALOX5 (0.42) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL26435559 0.88 ALOX5 (0.38) ALOX5SIRT2SIRT1GGPS1PRKDC
SCHEMBL26435710 0.88 ALOX5 (0.36) ALOX5SIRT2SIRT1PRKDCPIK3CD
SCHEMBL26435709 0.88 ALOX5 (0.36) ALOX5SIRT2SIRT1PRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 ALOX5 1266/4885SIRT2 3665/4885SIRT1 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.