Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19098594 | 0.84 | NCF1 (0.41) | SIGMAR1 | |
| SCHEMBL17888398 | 0.81 | SIGMAR1 (0.41) | SIGMAR1HTR2AHRH1 | |
| SCHEMBL26148766 | 0.78 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL2915291 | 0.78 | — | — | |
| SCHEMBL24172020 | 0.76 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL12049729 | 0.76 | NCF1 (0.48) | SIGMAR1 | |
| SCHEMBL2915294 | 0.76 | CHKA (0.36) | — | |
| SCHEMBL3678351 | 0.76 | — | — | |
| SCHEMBL14820100 | 0.74 | — | — | |
| SCHEMBL23559768 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |